i.Mune NEO* is a quantitative test to determine the percentages of lymphocyte subsets in capillary whole blood specimens from newborns dried on filter paper
i.Mune NEO* is suitable for epigenetic quantification of:
in dried blood spot (DBS) samples from newborns
A cohort of 250 apparently healthy newborns and 24 confirmed SCID and XLA cases was analyzed using epigenetic immune cell quantification of T-, B- and NK cells in dried blood spot samples2)
23 out of 24 confirmed SCID or XLA cases were correctly identified using the epigenetic immune cell quantification method.
Using combined TREC/KREC Analysis, 22 out of 24 cases were correctly identified2)
Epigenetic immune cell quantification identifies false-positive SCID screening cases (Blom et al., 2021)1)
*i.Mune NEO is for research use, only and has not been registered as an IVD product and has not been approved or cleared by a regulatory authority.
**The above clinical applications are currently tested in several studies